NFL odds, lines, picks, top predictions for Week 1, 2021: Football model backing 49ers, Panthers
Written by Luck on September 10, 2021
Baltimore was already without starting running back J.K. Dobbins due to a season-ending knee injury. Backup Gus Edwards went down with a potentially significant knee injury on Thursday, leaving the Ravens in a tough spot heading into the Week 1 NFL schedule. They are currently listed as four-point favorites at Las Vegas in the latest Week 1 NFL odds from Caesars Sportsbook. Should you back the Raiders with your Week 1 NFL predictions? Baltimore and Las Vegas will wrap up the opening week of the season on Monday Night Football. All of the Week 1 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and predictions you need to make the best Week 1 NFL picks now.
The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters the 2021 season on an incredible 120-78 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the Top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, it has turned its attention to the latest Week 1 NFL odds from Caesars and locked in picks for every NFL matchup. Head here to see every pick.
Top Week 1 NFL predictions
One of the top Week 1 NFL predictions the model recommends: The 49ers (-7.5) cover the spread against the Lions. Despite dealing with injuries to key players like Nick Bosa, Dee Ford and others, San Francisco still managed to have one of the league’s most successful defenses in 2020. In fact, the 49ers gave up just 314.4 yards per game, which ranked fifth in the NFL.
Bosa is on track to play against Detroit in Week 1 after suffering a season-ending knee injury a season ago. The 2019 Defensive Rookie of the Year will certainly cause havoc against a Detroit offense that averaged just 93.7 rushing yards per game last season, which ranked 30th in the NFL. The model shows San Francisco’s defense holding Detroit to just 66 rushing yards, resulting in the 49ers covering the spread in nearly 60 percent of simulations.
Another one of the top Week 1 NFL picks from the model: The Panthers (-5.5) cover as home favorites against the Jets. Quarterback Sam Darnold has never had much power alongside him during his NFL career, but now he has star running back Christian McCaffrey in the backfield. McCaffrey missed most of last season and was taken as the No. 1 overall Fantasy football pick in most drafts. Darnold has the revenge factor on his side as he gets ready to go up against his former team.
New York is playing under a first-year head coach, so it will take the Jets time to develop chemistry. They have a shaky secondary that Darnold should have success against. SportsLine’s model has Carolina covering this number in well over 50 percent of simulations.
How to make Week 1 NFL picks
The model has also made the call on who wins and covers in every other game on the Week 1 NFL schedule, and it’s calling for a Super Bowl contender to go down hard. You can only get every pick for every game at SportsLine.
So what NFL picks can you make with confidence? And which Super Bowl contender goes down hard? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $7,900 since its inception, and find out.
Week 1 NFL odds (via Caesars)
Sunday, Sept. 12
Steelers at Bills (-6.5, 48.5)
Featured Game | Buffalo Bills vs. Pittsburgh Steelers
Jets at Panthers (-5.5, 44.5)
Featured Game | Carolina Panthers vs. New York Jets
Jaguars at Texans (+2.5, 44.5)
Featured Game | Houston Texans vs. Jacksonville Jaguars
Featured Game | Tennessee Titans vs. Arizona Cardinals
Chargers at Washington (+1, 44.5)
Featured Game | Washington Football Team vs. Los Angeles Chargers
Featured Game | Atlanta Falcons vs. Philadelphia Eagles
Seahawks at Colts (+2.5, 49.5)
Featured Game | Indianapolis Colts vs. Seattle Seahawks
Featured Game | Cincinnati Bengals vs. Minnesota Vikings
49ers at Lions (+7.5, 45)
Featured Game | Detroit Lions vs. San Francisco 49ers
Featured Game | Kansas City Chiefs vs. Cleveland Browns
Dolphins at Patriots (-3, 43.5)
Featured Game | New England Patriots vs. Miami Dolphins
Featured Game | New York Giants vs. Denver Broncos
Featured Game | New Orleans Saints vs. Green Bay Packers
Featured Game | Los Angeles Rams vs. Chicago Bears
Monday, Sept. 13
Ravens at Raiders (+4.5, 50.5)
Featured Game | Las Vegas Raiders vs. Baltimore Ravens
require.config({“baseUrl”:”https://sportsfly.cbsistatic.com/fly-054/bundles/sportsmediajs/js-build”,”config”:{“version”:{“fly/components/accordion”:”1.0″,”fly/components/alert”:”1.0″,”fly/components/base”:”1.0″,”fly/components/carousel”:”1.0″,”fly/components/dropdown”:”1.0″,”fly/components/fixate”:”1.0″,”fly/components/form-validate”:”1.0″,”fly/components/image-gallery”:”1.0″,”fly/components/iframe-messenger”:”1.0″,”fly/components/load-more”:”1.0″,”fly/components/load-more-article”:”1.0″,”fly/components/load-more-scroll”:”1.0″,”fly/components/loading”:”1.0″,”fly/components/modal”:”1.0″,”fly/components/modal-iframe”:”1.0″,”fly/components/network-bar”:”1.0″,”fly/components/poll”:”1.0″,”fly/components/search-player”:”1.0″,”fly/components/social-button”:”1.0″,”fly/components/social-counts”:”1.0″,”fly/components/social-links”:”1.0″,”fly/components/tabs”:”1.0″,”fly/components/video”:”1.0″,”fly/libs/easy-xdm”:”2.4.17.1″,”fly/libs/jquery.cookie”:”1.2″,”fly/libs/jquery.throttle-debounce”:”1.1″,”fly/libs/jquery.widget”:”1.9.2″,”fly/libs/omniture.s-code”:”1.0″,”fly/utils/jquery-mobile-init”:”1.0″,”fly/libs/jquery.mobile”:”1.3.2″,”fly/libs/backbone”:”1.0.0″,”fly/libs/underscore”:”1.5.1″,”fly/libs/jquery.easing”:”1.3″,”fly/managers/ad”:”2.0″,”fly/managers/components”:”1.0″,”fly/managers/cookie”:”1.0″,”fly/managers/debug”:”1.0″,”fly/managers/geo”:”1.0″,”fly/managers/gpt”:”4.3″,”fly/managers/history”:”2.0″,”fly/managers/madison”:”1.0″,”fly/managers/social-authentication”:”1.0″,”fly/utils/data-prefix”:”1.0″,”fly/utils/data-selector”:”1.0″,”fly/utils/function-natives”:”1.0″,”fly/utils/guid”:”1.0″,”fly/utils/log”:”1.0″,”fly/utils/object-helper”:”1.0″,”fly/utils/string-helper”:”1.0″,”fly/utils/string-vars”:”1.0″,”fly/utils/url-helper”:”1.0″,”libs/jshashtable”:”2.1″,”libs/select2″:”3.5.1″,”libs/jsonp”:”2.4.0″,”libs/jquery/mobile”:”1.4.5″,”libs/modernizr.custom”:”2.6.2″,”libs/velocity”:”1.2.2″,”libs/dataTables”:”1.10.6″,”libs/dataTables.fixedColumns”:”3.0.4″,”libs/dataTables.fixedHeader”:”2.1.2″,”libs/dateformat”:”1.0.3″,”libs/waypoints/infinite”:”3.1.1″,”libs/waypoints/inview”:”3.1.1″,”libs/waypoints/jquery.waypoints”:”3.1.1″,”libs/waypoints/sticky”:”3.1.1″,”libs/jquery/dotdotdot”:”1.6.1″,”libs/jquery/flexslider”:”2.1″,”libs/jquery/lazyload”:”1.9.3″,”libs/jquery/maskedinput”:”1.3.1″,”libs/jquery/marquee”:”1.3.1″,”libs/jquery/numberformatter”:”1.2.3″,”libs/jquery/placeholder”:”0.2.4″,”libs/jquery/scrollbar”:”0.1.6″,”libs/jquery/tablesorter”:”2.0.5″,”libs/jquery/touchswipe”:”1.6.18″,”libs/jquery/ui/jquery.ui.core”:”1.11.4″,”libs/jquery/ui/jquery.ui.draggable”:”1.11.4″,”libs/jquery/ui/jquery.ui.mouse”:”1.11.4″,”libs/jquery/ui/jquery.ui.position”:”1.11.4″,”libs/jquery/ui/jquery.ui.slider”:”1.11.4″,”libs/jquery/ui/jquery.ui.sortable”:”1.11.4″,”libs/jquery/ui/jquery.ui.touch-punch”:”0.2.3″,”libs/jquery/ui/jquery.ui.autocomplete”:”1.11.4″,”libs/jquery/ui/jquery.ui.accordion”:”1.11.4″,”libs/jquery/ui/jquery.ui.tabs”:”1.11.4″,”libs/jquery/ui/jquery.ui.menu”:”1.11.4″,”libs/jquery/ui/jquery.ui.dialog”:”1.11.4″,”libs/jquery/ui/jquery.ui.resizable”:”1.11.4″,”libs/jquery/ui/jquery.ui.button”:”1.11.4″,”libs/jquery/ui/jquery.ui.tooltip”:”1.11.4″,”libs/jquery/ui/jquery.ui.effects”:”1.11.4″,”libs/jquery/ui/jquery.ui.datepicker”:”1.11.4″}},”shim”:{“liveconnection/managers/connection”:{“deps”:[“liveconnection/libs/sockjs-0.3.4″]},”liveconnection/libs/sockjs-0.3.4”:{“exports”:”SockJS”},”libs/setValueFromArray”:{“exports”:”set”},”libs/getValueFromArray”:{“exports”:”get”},”fly/libs/jquery.mobile-1.3.2″:[“version!fly/utils/jquery-mobile-init”],”libs/backbone.marionette”:{“deps”:[“jquery”,”version!fly/libs/underscore”,”version!fly/libs/backbone”],”exports”:”Marionette”},”fly/libs/underscore-1.5.1″:{“exports”:”_”},”fly/libs/backbone-1.0.0″:{“deps”:[“version!fly/libs/underscore”,”jquery”],”exports”:”Backbone”},”libs/jquery/ui/jquery.ui.tabs-1.11.4″:[“jquery”,”version!libs/jquery/ui/jquery.ui.core”,”version!fly/libs/jquery.widget”],”libs/jquery/flexslider-2.1″:[“jquery”],”libs/dataTables.fixedColumns-3.0.4″:[“jquery”,”version!libs/dataTables”],”libs/dataTables.fixedHeader-2.1.2″:[“jquery”,”version!libs/dataTables”],”https://sports.cbsimg.net/js/CBSi/app/VideoPlayer/AdobePass-min.js”:[“https://sports.cbsimg.net/js/CBSi/util/Utils-min.js”]},”map”:{“*”:{“adobe-pass”:”https://sports.cbsimg.net/js/CBSi/app/VideoPlayer/AdobePass-min.js”,”facebook”:”https://connect.facebook.net/en_US/sdk.js”,”facebook-debug”:”https://connect.facebook.net/en_US/all/debug.js”,”google”:”https://apis.google.com/js/plusone.js”,”google-platform”:”https://apis.google.com/js/client:platform.js”,”google-csa”:”https://www.google.com/adsense/search/async-ads.js”,”google-javascript-api”:”https://www.google.com/jsapi”,”google-client-api”:”https://apis.google.com/js/api:client.js”,”gpt”:”https://securepubads.g.doubleclick.net/tag/js/gpt.js”,”newsroom”:”https://c2.taboola.com/nr/cbsinteractive-cbssports/newsroom.js”,”recaptcha”:”https://www.google.com/recaptcha/api.js?onload=loadRecaptcha&render=explicit”,”recaptcha_ajax”:”https://www.google.com/recaptcha/api/js/recaptcha_ajax.js”,”supreme-golf”:”https://sgapps-staging.supremegolf.com/search/assets/js/bundle.js”,”taboola”:”https://cdn.taboola.com/libtrc/cbsinteractive-cbssports/loader.js”,”twitter”:”https://platform.twitter.com/widgets.js”,”video-avia”:”https://vidtech.cbsinteractive.com/avia-js/1.9.0/player/avia.min.js”,”video-avia-cvui”:”https://vidtech.cbsinteractive.com/avia-js/1.9.0/legacy/cvui/cvui.min.js”,”video-cvp”:”https://vidtech.cbsinteractive.com/cvp/1.2.2/cvp.min.js”,”video-cvui”:”https://vidtech.cbsinteractive.com/cvp/1.2.2/cvui.min.js”,”video-ima3″:”https://imasdk.googleapis.com/js/sdkloader/ima3.js”,”video-ima3-dai”:”https://imasdk.googleapis.com/js/sdkloader/ima3_dai.js”,”video-utils”:”https://sports.cbsimg.net/js/CBSi/util/Utils-min.js”,”video-vast-tracking”:”https://vidtech.cbsinteractive.com/sb55/vast-js/vtg-vast-client.js”}},”waitSeconds”:300});
